Common pain medication may be linked to higher dementia risk
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Gabapentin, often used as a safer alternative to opioids for low back pain, may be linked to a slightly higher risk of dementia and mild cognitive impairment (MCI). A recent study in Regional Anesthesia & Pain Medicine found that gabapentin use was associated with cognitive issues within 10 years, with more frequent use linked to a higher risk. While gabapentin can be effective for pain relief, it’s important to discuss potential cognitive effects with your healthcare provider and monitor memory over time.
Source
Eghrari, N. B., Yazji, I. H., Yavari, B., Van Acker, G. M., & Kim, C. H. (2025). Risk of dementia following gabapentin prescription in chronic low back pain patients. Regional Anesthesia and Pain Medicine. https://doi.org/10.1136/rapm-2025-106577
Additional Reading
https://www.newsweek.com/common-pain-drug-linked-higher-dementia-risk-2097169
https://www.aol.com/lifestyle/common-back-pain-medication-linked-160700186.html