Experimental cholesterol drug may protect against Alzheimer’s
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New results from a large clinical trial suggest that an experimental drug originally developed for cardiovascular disease may also help prevent Alzheimer’s. The findings indicate the treatment could reduce markers associated with cognitive decline, offering a potential dual benefit. Researchers caution that further studies are needed to confirm its safety and effectiveness in targeting Alzheimer’s.
Source
Bateman RJ, Li Y, McDade EM, et al. Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial. Preprint. medRxiv. 2025;2024.10.29.24316289. Published 2025 Jan 29. doi:10.1101/2024.10.29.24316289
Additional Reading
https://www.statnews.com/2025/07/30/new-amsterdam-pharma-cholesterol-drug-alzheimers/
https://medicine.washu.edu/news/anti-amyloid-drug-shows-signs-of-preventing-alzheimers-dementia/