New Alzheimer’s blood test focuses on early memory changes

Researchers are exploring new ways to detect Alzheimer’s earlier, shifting the focus from brain plaques to subtle changes in thinking and memory. A newly developed blood test may help identify whether the disease is beginning to affect cognitive function. Rather than relying solely on amyloid, a protein long linked to Alzheimer’s, the test reflects a growing interest in finding more accurate biomarkers, measurable signs in the body that could offer clearer insight into the disease’s progression.

Source

Horie, K., Salvadó, G., Koppisetti, R.K. et al. Plasma MTBR-tau243 biomarker identifies tau tangle pathology in Alzheimer’s disease. Nat Med (2025). https://doi.org/10.1038/s41591-025-03617-7

Additional Reading

https://www.npr.org/sections/shots-health-news/2025/04/02/g-s1-57688/alzheimers-blood-spinal-fluid-tests-memory-loss-brain-plaques

https://time.com/7273006/alzheimers-disease-blood-test-tau/

https://www.cnn.com/2025/04/07/health/alzheimer-risk-blood-biomarkers-wellness

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